姓　名：李娟娟

职　称：教授（高聘）

E-mail：lijuanjuan@hainanu.edu.cn

一、个人基本情况

李娟娟，博士，教授（高聘）。

二、教育经历

2023.10至今 永利y l65335 教授（高聘）

2021.10-2023.09 海南老员工命科学学院 教授（高聘）

2019-2021 上海交通大学医学院附属仁济医院 博士后（合作导师：刘尽尧 研究员）

2016-2019 中国地质大学（北京） 博士

三、科研情况

发表论文20余篇，主持博士后创新人才支持计划1项，永利集团科研启动基金项目1项，永利集团科研启动基金项目1项，国家自然科学基金地区基金1项，海南省自然科学基金1项，海南省高等学校科学研究一般项目1项。

四、研究领域

微生物化学组装与医用材料开发

1. 益生菌表面修饰及其生物应用

2. 生物医学材料的制备与应用

五、代表性项目

1. 博士后创新人才支持计划（编号：BX2020216），2019-2021，已结题，主持

2. 永利集团高层次人才启动项目（80万），2021-2026，在研，主持

3. 国家自然科学基金地区项目（编号32260020），在研，主持

4. 海南省自然科学基金青年基金面上项目（编号322MS027），在研，主持

5. 海南省高等学校科学研究一般项目（编号Hnky2022-8），在研，主持

六、代表性成果

1. Yong Liu*, Ruyue Wang, Kaiyuan Wang, Fei Yang, Yundi Chen, Wenwen Xie, Shengxu Luo*, Zhenyi Liang, Qian Wang*, Juanjuan Li*, Cuttlefish Ink Nanoparticles-Integrated Aerogel Membranes for Efficient Solar Steam Generation, RSC Sustainability, 2024, 10.1039/D3SU00301A.

2. Yanxue Si, Huize Luo, Pai Zhang, Chuangliang Zhang, Juanjuan Li*, Peng Jiang*, Wenbing Yuan*, Ruitao Cha*, CD-MOFs: From preparation to drug delivery and therapeutic application. Carbohydrate Polymers, 2024, 323, 121424.

3. Yutong Cui, Jiani Han, Hong Li, Xiang Ma, Yangqiong Tang, Yong Deng, Dayong Wang, Denggao Huang, Juanjuan Li*, Zhu Liu*, Ultrasound mediated gold nanoclusters-capped gas vesicles for enhanced fluorescence imaging, Photodiagnosis and Photodynamic Therapy, 2023, 42, 103737.

4. Yong Liu*, Fei Yang, Zixin Pan, Zhenzhen Fu, Xiaoli Jiang, Zhenping Cao*, Juanjuan Li*, Hao Wang*, Gallium-Enabled Bactericidal Medicine. Materials Today, 2023, 67, 548-565.

5. Yunxiang Yan#, Yong Liu#, Juanjuan Li*, Ye Li, Haoheng Wu, Hong Li, Xiang Ma, Yanqiong Tang, Yuan Tong, Kexian Yi, Quanfeng Liang, Zhu Liu*. A Molecular Switch-Integrated Nanoplatform Enables Photo-Unlocked Antibacterial Drug Delivery for Synergistic Abscess Therapy. Advanced Healthcare Materials, 2023, 2301157.

6. Yong Liu, Wenqin Yu, Qian Wang*, Zhenping Cao*, Juanjuan Li*. Artificially engineered bacteria to treat gastrointestinal disease and cancer. Drug Discovery Today, 2023, 28, 103667.

7. Juanjuan Li*, Jiani Han, Wenqin Yu, Kaiyuan Wang, Zhu Liu*, Yong Liu*. Alginate-modulated continuous assembly of iron/tannic acid composites as photothermally responsive wound dressings for hemostasis and drug resistant bacteria eradication. International Journal of Biological Macromolecules, 2023, 242, 124886.

8. Juanjuan Li, Zhenzhen Fu, Yong Liu*. Encapsulation of liquid metal nanoparticles inside metal–organic frameworks for hydrogel-integrated dual functional biotherapy. Chemical Engineering Journal, 2023, 457, 141302.

9. Yunxiang Yan, Ye Li, Hong Li, Xiang Ma, Yanqiong Tang, Kexian Yi, Xiangmin Lin, Juanjuan Li*, Zhu Liu*. Antimicrobial Zeolitic Imidazolate Frameworks with Dual Mechanisms of Action. ACS Infectious Diseases, 2023, 9, 507-517.

10. Zhenfei Xu, Xiaoli Jiang, Ye Li, Xiang Ma, Yanqiong Tang, Hong Li, Kexian Yi, Juanjuan Li*, Zhu Liu*. Antifungal Activity of Montmorillonite/Peptide Aptamer Nanocomposite against Colletotrichum gloeosporioides on Stylosanthes. International Journal of Biological Macromolecules, 2022, 217, 282-290.

11. Juanjuan Li#, Qing Xia#, Haiyan Guo, Zhenzhen Fu, Yong Liu, Sisi Lin, Jinyao Liu*, Decorating Bacteria with Triple Immune Nanoactivators Generates Tumor-Resident Living Immunotherapeutics. Angewandte Chemie-International Edition, 2022, e202202409.

12. Juanjuan Li#, Weiliang Hou#, Sisi Lin, Chao Pan, Lu Wang, Feng Wu, Jinyao Liu*, Polydopamine Nanoparticle-mediated Dopaminergic Immunoregulation in Colitis. Advanced Science, 2021, 202104006.

13. Weiliang Hou#, Juanjuan Li#, Zhenping Cao, Sisi Lin, Chao Pan, Yan Pang*, Jinyao Liu*, Decorating Bacteria with a Therapeutic Nanocoating for Synergistically Enhanced Biotherapy. Small, 2021, 2101810.

14. Juanjuan Li, Ruitao Cha*, Huize Luo, Wenshuai Hao, Yan Zhang*, Xingyu Jiang*, Nanomaterials for Theranostic of Obesity. Biomaterials, 2019, 223, 119474.

15. Juanjuan Li, Ruitao Cha*, Xiaohui Zhao, Hongbo Guo, Mingzheng Wang, Fengshan Zhou*, Xingyu Jiang*, Gold Nanoparticles Cure Bacterial Infection with Benefit to Intestinal Microflora. ACS Nano, 2019, 13, 5002-5014.

16. Juanjuan Li, Ruitao Cha*, Keiwen Mou, Xiaohui Zhao, Keying Long, Huize Luo, Fengshan Zhou*, Xingyu Jiang*, Nanocellulose-Based Antibacterial Materials. Advanced Healthcare Materials, 2018, 7, 1800334.

17. Juanjuan Li, Ruitao Cha*, Yulong Zhang, Hongbo Guo, Keying Long, Pangye Gao, Xiaohui Wang*, Fengshan Zhou*, Xingyu Jiang*, Iron Oxide Nanoparticles for Targeted Imaging of Liver Tumor with Ultralow Hepatotoxicity, Journal of Materials Chemistry B, 2018, 6, 6413-6423.

18. Ruitao Cha*,#, Juanjuan Li #, Yang Liu#, Yapei Zhang, Qian Xie*, Mingming Zhang*, Fe3O4 Nanoparticles Modified by CD-Containing Star Polymer for MRI and Drug Delivery. Colloids and surfaces. B, Biointerfaces, 2017, 158, 213-221.

19. Huashan Wang#, Juanjuan Li #, Xiaoqing Zhang#, Binfeng Hu#, Yang Liu, Lin Zhang, Ruitao Cha*, Jiashu Sun*, Xingyu Jiang*, A Microfluidic Indirect Competitive Immunoassay for Multiple and Sensitive Detection of Testosterone in Serum and Urine. Analyst, 2016, 141, 815-819.

20. Juanjuan Li #, Yang Liu#, Ruitao Cha*, Bei Ran, Keiwen Mou, Huashan Wang, Qian Xie*, Jiashu Sun*, Xingyu Jiang*, The Biocompatibility Evaluation of Iron Oxide Nanoparticles Synthesized by a One Pot Process for Intravenous Iron Supply. RSC Advances, 2016, 6, 14329-14334.